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Although the World Health Organization listed Cannabidiolum in a list of International Nonproprietary Names for Pharmaceutical Substances (INN) on 30 June 2016. French and Spanish versions wrongly mention agonist action of CBD on cannabinoid receptors while the English version says CBD is a cannabinoid receptor antagonist.[citation needed]
Cannabis has been cultivated by humans, for a variety of purposes, since antiquity. So it comes as no surprise that there are several different species and even different varieties within the species, depending on the purpose the plants were bred for. Through artificial selection, different species of cannabis have different properties–some have been used for medicinal purposes, others as food, and others to create clothes, ropes, and other items.
At the federal level, CBD is classified as a Schedule 1 drug in the United States because it is one of the many cannabinoids present in marijuana. To be labeled a schedule 1 drug means that it has a high potential for abuse and the potential to create severe psychological or physical dependence; therefore these drugs are not allowed to be used for medical use.
Valenti M, Massi P, Bolognini D, et al. Cannabidiol, a non-psychoactive cannabinoid compound inhibits human glioma cell migration and invasiveness. 34th National Congress of the Italian Society of Pharmacology 2009.
As explained earlier, CBD has potent anti-inflammatory effects. And thanks to this CBD may give people arthritis relief and joint pain relief. Cannabidiol does this by reducing pain, swelling and you may see reduced joint destruction, along with slower disease progression of your arthritis. In one animal study, CBD was able to protect joints from severe damage and showed an improvement in arthritis symptoms. Another controlled study ran for five weeks and showed excellent improvements in lowering pain, improving sleep quality and inflammation.
Jump up ^ Campos AC, Guimarães FS (August 2008). “Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats”. Psychopharmacology. 199 (2): 223–30. doi:10.1007/s00213-008-1168-x. PMID 18446323.
Another study published in Current Pharmaceutical Design found that CBD may have similar effects to certain antipsychotic drugs and that it may be safe and effective in treating patients with schizophrenia.
Mr. Chairman, Ms. Chairwoman, and Members of the Senate Drug Caucus, thank you for inviting the National Institute on Drug Abuse (NIDA), a component of the National Institutes of Health (NIH), to participate in this hearing to share what we know about the biology and the potential therapeutic effects of cannabidiol (CBD), one of the main active chemical compounds found in marijuana. In light of the rapidly evolving interest in the potential use of marijuana and its derivative compounds for medical purposes, it is important to take stock of what we know and do not know about the therapeutic potential of CBD.
For a convenient way to get your daily CBD, Real Scientific Hemp Oil™ Liquids contain our all-natural and pure cannabidiol combined with medium chain triglyceride (MCT) oil. Naturally abundant in fatty acids, MCT oil is sourced from sustainably cultivated palm oil and organic coconut oil and comprised of 60% Caprylic Acid and 40% Capric Acid.
THC works on the endocannabinoid system in a different way from CBD, so although it is a similar compound, it does not have these benefits.  However, research has shown that THC can have a positive influence over pain relief, PTSD, poor appetite and more.
CBD Oil is the fastest growing natural remedy on the market today and for a good reason. But you may be asking does it work? And, what may it help with? Cannabidiol is made from the hemp plant. But not just any old hemp plant. Good CBD Hemp oil is made from high CBD, low THC (tetrahydrocannabinol) hemp plants. Unlike Marijuana based products that are produced from different plants containing high amounts of THC and are considered illegal. However, because Cannabidiolproducts are derived from the purposely grown hemp plant, there are only trace amounts of THC. THC is the psychoactive ingredient found in Marijuana based products. There are currently over 85 known cannabinoids, with THC and CBD being the most common in Marijuana.
Targeting the eCB system through the use of the commercially available oromucosal spray Sativex, a combination of the phytocannabinoids cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), has already proved beneficial for the treatment of neuropathic pain and spasticity in multiple sclerosis (Nurmikko et al., 2007; Notcutt et al., 2012). Furthermore, in a number of clinical trials modulation of the eCB system has improved behavioral symptoms in AD patients. In patients diagnosed with probable AD, a twice daily dose of 2.5 mg dronabinol, a phytocannabinoid derived from THC, was shown to reduce weight loss and improve disturbed behavior with minimal side effects of euphoria, drowsiness, and tiredness (Volicer et al., 1997). A more recent study has shown that in patients with late-stage AD, a single daily 2.5 mg dose of dronabinol improved nocturnal aggression and agitation with no adverse side effects (Walther et al., 2006). A single case study has also reported a reduction in the severity of agitation and resistiveness in a patient with mild AD through the use of nabilone, a CB1 receptor agonist (Passmore, 2008). Furthermore, ongoing placebo-controlled double-blind phase II clinical trials are being carried out on the safety and efficacy of Namisol, an oral tablet containing THC, in patients suffering from AD and vascular dementia. Measurable outcomes from these two studies include any alteration in neuropsychiatric symptoms, agitation, balance and mobility, pain, quality of life, and episodic memory (Rikkert, 2014a,b). To date, no clinical studies have been carried out on the effectiveness of these drugs on abrogating neurodegenerative processes in AD. There is, however, a wealth of preclinical data outlining the beneficial effects of cannabinoid treatment on neuroinflammation, excitotoxicity, oxidative stress, and neurodegeneration that may be of relevance to AD.

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Additionally, several animal studies have demonstrated that CBD may help reduce the inflammation and cell death associated with heart disease due to its powerful antioxidant and stress-reducing properties.
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Different states also require different levels of prescription to possess and use CBD oil. In Missouri, for example, a person must show that three other treatment options have been unsuccessful in treating epilepsy.
xx Di Marzo and Centonze . Placebo effects in a multiple sclerosis spasticity enriched clinical trial with the oromucosal cannabinoid spray (THC/CBD): dimension and possible causes. CNS Neurosci Ther. 21(3):215-21. (2015).
In nature, Cannabis ruderalis typically has the lowest levels of THC, Cannabis sativa has a higher level of THC than it has CBD, and Cannabis indica has a higher level of CBD than it has THC. However, since man has been cultivating cannabis (and especially Cannabis sativa) for thousands of years, the effects of artificial selections have led to several different types of cannabis even within the same species, depending on the purpose the cannabis was cultivated for.
Hemp seed oil is an extract from the seeds of industrial hemp. Industrial hemp is the only plant used in crafting this type of hemp oil. Hemp seeds are cold pressed, peeled or unpeeled, to create a delicious nutty oil.
Technically, CBD and its sister cannabinoid compounds are classified as phytocannabinoids, which means that they’re derived from plants. But there are also several other types of cannabinoids you should know about too.
On May 16, 2014, Tennessee Governor Bill Haslam signed SB 2531 into law. The bill allows the use of cannabis oil containing cannabidiol (CBD) that has less than 0.9% THC “as part of a clinical research study on the treatment of intractable seizures when supervised by a physician practicing at… a university having a college or school of medicine.” The study is authorized for four years.
-These days, pharmaceutical companies are producing CBD oils through scientific extraction processes that separate harmful solvents from the pure oil. Hemp oil may use safer extraction methods, but since far less CBD is produced with the finished product, hemp-based CBDs are still considered inferior to CBD’s derived from the whole cannabis plant.
CBD seems to have anti-cancer properties, too. At the California Pacific Medical Center Research Institute in San Francisco, researchers Sean McAllister and Pierre Desprez have found that CBD can block cancer cells from metastasizing.
Dixie Botanicals® offers a collection of soy-free and vegetarian CBD hemp tincture oil available in a variety of flavors and packaged in a sleek vial meant to carry on the go. The Dixie Botanicals CBD hemp oil drops are available in natural, peppermint and cinnamon flavors.
Cannabidiol (CBD) is one of the 400+ ingredients found in marijuana and is not psychoactive. Many states have passed laws allowing for the use of a CBD extract, usually in oil form, with minimal tetrahydrocannabinol (THC), and often for the treatment of epilepsy or seizures in seriously ill children.
For example, the cannabinoids produced within the body’s endocannabinoid system are known as endocannabinoids (such as arachidonoylethanolamine, virodhamine, and many others). There are also cannabinoids manufactured via chemical reactions in laboratories, known as synthetic cannabinoids.
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