Watzl, B., Scuderi, P., and Watson, R. R. Marijuana components stimulate human peripheral blood mononuclear cell secretion of interferon-gamma and suppress interleukin-1 alpha in vitro. Int J Immunopharmacol. 1991;13(8):1091-1097. View abstract.
Jump up ^ Ryberg E, Larsson N, Sjögren S, Hjorth S, Hermansson NO, Leonova J, Elebring T, Nilsson K, Drmota T, Greasley PJ (December 2007). “The orphan receptor GPR55 is a novel cannabinoid receptor”. British Journal of Pharmacology. 152 (7): 1092–101. doi:10.1038/sj.bjp.0707460. PMC 2095107 . PMID 17876302.
Collin, C., Davies, P., Mutiboko, I. K., and Ratcliffe, S. Randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis. Eur.J.Neurol. 2007;14(3):290-296. View abstract.
^ Jump up to: a b Scuderi C, Filippis DD, Iuvone T, Blasio A, Steardo A, Esposito G (May 2009). “Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders”. Phytotherapy Research (Review). 23 (5): 597–602. doi:10.1002/ptr.2625. PMID 18844286.
Glad you asked! Cannabinoids are the primary chemical compounds found in hemp and all cannabis plants. The two you have probably heard of are CBD and THC. CBD is the best known non-psychoactive cannabinoid, and tetrahydrocannabinol (THC) is the only psychoactive cannabinoid. Hemp oil contains only trace amounts of THC (less than .3%).
In this article, we are putting the most important facts surrounding Cannabidiol together to cut through some of the confusion and give you a clearer picture about this new cannabinoid known as CBD. This article covers:
For Lisa Leyden, Jackson’s mother, these issues don’t negate the compound’s enormous potential. “I realize this isn’t perfect,” she says. “We absolutely need to know more. But in the meantime, many people need help. They’re in bad shape, and this seems to work.”
This article may contain certain forward-looking statements and information, as defined within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, and is subject to the Safe Harbor created by those sections. This material contains statements about expected future events and/or financial results that are forward-looking in nature and subject to risks and uncertainties. Such forward-looking statements by definition involve risks, uncertainties.
On June 2, 2014, South Carolina Governor Nikki Haley signed S 1035into law. “Julian’s Law” pertains to people who obtain a written certification signed by a physician “stating that the patient has been diagnosed with Lennox-Gastaut Syndrome, Dravet Syndrome, also known as ‘severe myoclonic epilepsy of infancy’, or any other severe form of epilepsy that is not adequately treated by traditional medical therapies and the physician’s conclusion that the patient might benefit from the medical use of cannabidiol.” Those patients may use CBD oil that is less than 0.9% THC and more than 15% cannabidiol, which is to be provided by the Medical University of South Carolina in a study to determine the effects of CBD on controlling seizures.
Confusion about the difference between hemp and cannabis oil has spiked recently due to the increase of cannabis-based products available on the market. Variety is a great thing considering every individual requires different concentrations and delivery methods. If you are new to cannabis vape oils or products, it can be difficult to know what is what.
It would seem that the strong research supporting the hemp oil benefits, its safety and ease of use and purchase puts it in front of cannabis CBD when comparing the two. Whilst cannabis CBD does have its benefits, its drawbacks seem to outweigh these, and given the positives of hemp CBD and its lack of drawbacks hemp CBD seems a clear winner.
Decades of research indicate that cannabinoids like CBD interact with the body’s endocannabinoid system, a complex system that contributes to a variety of biological processes like inflammation responses, relaxation, sleeping, and appetite. By linking with the two main types of cannabinoid receptors, CB1 and CB2, which are found on cells throughout the body, CBD interacts with the endocannabinoid system, helping it in the regulation of homeostasis — the body’s natural state of balance.
Wade, D. T., Makela, P., Robson, P., House, H., and Bateman, C. Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients. Mult.Scler. 2004;10(4):434-441. View abstract.
CBD was isolated from the cannabis plant in 1940 independently by Adams and Todd and their colleagues. They assessed CBD and considered it to be biologically inactive. The chemical structure of CBD was fully established in 1963 by Mechoulam and Shvo.
The World Health Organisation has stated depression as the most significant disability in the world and anxiety ranks 6th. We all know anxiety and depression are typically treated with pharmaceutical drugs. These drugs often come with unwanted side effects like insomnia, sexual dysfunction, drowsiness and these are just a few of them. Furthermore, and probably the worst effect of these pharmaceutical drugs is people become dependent upon them. This dependency is severe and unwanted by most people suffering from anxiety or depression, but something that’s unavoidable.
Morgan, C. J., Das, R. K., Joye, A., Curran, H. V., & Kamboj, S. K. (2013, June). Cannabidiol reduces cigarette consumption in tobacco smokers: Preliminary findings [Abstract]. Addictive Behaviors, 38(9), 2,433-2,436. Retrieved from www.ncbi.nlm.nih.gov/pubmed/23685330
Cannabinoids – A very diverse chemical family that includes natural as well as artificially created substances. Different cannabinoids have widely varied effects, with some cannabinoids proven to have soothing and relaxing properties and others classified as illegal drugs.
CBD seems to have anti-cancer properties, too. At the California Pacific Medical Center Research Institute in San Francisco, researchers Sean McAllister and Pierre Desprez have found that CBD can block cancer cells from metastasizing.
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The appeal? Proponents claim CBD can help ease pain, anxiety, depression and stress, boost focus and productivity, improve the immune system, reduce inflammation and more. And – unlike its psychoactive cousin THC – CBD, they say, is harmless, legal and can’t get you high. “The known is it’s good for you, it helps a lot of people and a lot of things, and you can’t hurt yourself,” says Phil Asquith, a farmer and producer of extra-virgin olive oil in California, who founded one of the first companies in the CBD space. “The unknown is all the details.”
Simply put, cannabinoids are naturally occurring compounds found in the cannabis plant. There are dozens of compounds including Cannabidiol (CBD), THC, and a host of other cannabinoids. Together they are responsible for the benefits and drawbacks to medical marijuana and industrial hemp-based products.
Jump up ^ Ujváry I, Hanuš L (2014). “Human Metabolites of Cannabidiol: A Review on Their Formation, Biological Activity, and Relevance in Therapy”. Cannabis and Cannabinoid Research. 1 (1): 90–101. doi:10.1089/can.2015.0012. PMC 5576600 . PMID 28861484.
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As mentioned above, cannabis and hemp differ in the levels of naturally occurring THC that they contain. THC is a cannabinoid like CBD. However, its properties are very different and often antagonistic to the effects of CBD. Hemp is naturally high in CBD and low in THC; the reverse is true of cannabis. In fact, hemp contains only about 0.3% – 1.5% THC, while cannabis contains about 5% – 10% or more THC.
According to the Utah Department of Health Hemp Registry, “To legally possess hemp extract under Utah law, an individual must apply for and obtain a hemp extract registration card from the Utah Department of Health, Office of Vital Records and Statistics (OVRS)”
The major (and arguably the only) difference between industrial hemp and medical marijuana is that industrial hemp is exclusively made from Cannabis sativa that was specifically bred to produce the lowest concentrations of THC possible.
I also would like to know which cbd oil you would suggest for chronic pain relief? Also does anyone know if it will affect fibroids in any way. Hemp worx sells what sounds like medicinal cbd oil but the label says hemp seed oil? Can any one tell me if this will work medicinally for pain relief
I purchased the 600 mg of pure kana. Overall i can say this has made a huge difference in my social life. I have not felt any kind of anxiety since taking the drops. I am about a month and a half in and on my second bottle. I wish purekana offered some kind of bundle deals or reward program since I know this is something worth purchasing monthly. Its always nice to save a little ?
Hey Matthew! Thanks for reaching out and asking. It depends on a lot of things, you would have to ask around to some CBD drink companies to find out more! Sorry I can’t be of more help, but good luck in your search 🙂
Mom went through chemo last year and now had a double mastectomy today.. May have to go through chemo again.. Trying to get her on cbd oil but she said she read that it’s not good for people with afib . Is this true ? Thanks !
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